MiR-199a-5p regulates rat liver regeneration and hepatocyte proliferation by targeting TNF-α TNFR1/TRADD/CASPASE8/CASPASE3 signalling pathway
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چکیده
منابع مشابه
MiR-199a Regulates Cell Proliferation and Survival by Targeting FZD7
A growing amount of evidence indicates that miRNAs are important regulators of multiple cellular processes and, when expressed aberrantly in different types of cancer such as hepatocellular carcinoma (HCC), play significant roles in tumorigenesis and progression. Aberrant expression of miR-199a-5p (also called miR-199a) was found to contribute to carcinogenesis in different types of cancer, inc...
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Recent advances in the study of microRNAs indicate that they have an important role in regulating cellular activities such as proliferation, morphogenesis, apoptosis and differentiation by regulating the expression of various genes. MiR-199a-3p is highly expressed in hair follicles and in some tumor cells, suggesting its participation in tumor progression, but it is significantly underexpressed...
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Liver regeneration (LR) after partial hepatectomy (PH) involves the proliferation and apoptosis of hepatocytes, and microRNAs have been shown to post-transcriptionally regulate genes involved in the regulation of these processes. To explore the role of miR-127 during LR, the expression patterns of miR-127 and its related proteins were investigated. MiR-127 was introduced into a rat liver cell l...
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Objective: Endometriosis is a chronic disease that influences approximately 5-15% of women of reproductive age. Some studies have confirmed that numerous microRNAs (miRNAs) are unconventionally expressed in the ectopic endometrium. However, the accurate pathological mechanism of the effect of miRNAs on endometriosis is not completely clear. The aim of this study was to investigate the functiona...
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ژورنال
عنوان ژورنال: Artificial Cells, Nanomedicine, and Biotechnology
سال: 2019
ISSN: 2169-1401,2169-141X
DOI: 10.1080/21691401.2019.1683566